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July 18, 2011

Thyroid Gland Replacement Therapy and Results

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That research found a double to triple expanded danger of fracture in individuals overaged seventy on higher dosages of thyroid gland replacement, particularly over 0.093 mg daily. In the past times, high thyroid gland replacement dosages have been demonstrated to be associated with decreased bone denseness and additional risk components for falls and faults. Bone cracks are rough on aged individuals, and that is why a research demonstrating extra dosages of thyroid gland endocrine replacement are associated with bone cracks should give you and the pause. (more…)

December 23, 2009

Synthetical Hormones in Menopause Women

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According to research workers, females using synthetical endocrines may have a multiplied chance of dying from lung carcinoma. Discoveries from the Women`s Wellness Initiative show that the apply of Prempro, a synthetic oestrogen coupled with a semisynthetic form of Lipo-Lutin, can head to a fifty-nine percent multiplied risk of death if a lady formulates non small-cell lung carcinoma. This was disclosed by Dr. Rowan Chlebowski of Harbor-UCLA health centre in the City of the Angels at the yearly meeting of the American Community of Clinical Oncology.

A research demonstrated that for non small-cell lung carcinoma, there was an important chance of dying if the females taking these semisynthetic endocrines developed carcinoma.

There were sixty-seven lung carcinoma fatals in the females taking Prempro and thirty-nine among those in the placebo category, according to Chlebowski. The females consuming the synthetic endocrines had an average survival rank of 9.4 calendar months while the selection rate of the females who took the placebo and got the disorder was 16.1 calendar months. (more…)

December 22, 2009

Menopause and its Ourcomes

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Menopause is a pattern shift in a woman’s life while her time period ceases. That’s why several humans call it “the menopause.” During climacterical period, a woman’s body slowly makes less of the endocrines oestrogen and progesterone. This frequently happens between the ages of forty-five and fifty-five. A woman has achieved climacterical period when she has not had a time period for twelve calendar months in a row and there are no additional reasons for this shift. (more…)

November 30, 2009

Symptomatic Menopause Highlighted In Evidence-Based Clinical Overview

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Expert Review of Neurotherapeutics has published a supplementary series of articles focusing on symptoms during the menopausal transition and the challenging treatment issues for the women involved. The reviews are currently freely available to any clinician at http://www.future-drugs.com/r/meno.

Some 42 million American women will be aged between 45 and 64 years by 2010, and this figure will rise to 47 million in 2050. Menopause is a natural phase of female development, which is uncomplicated in most women. However, it is estimated that at least 7 million women in the USA alone will present to primary care or gynecology for help with the more distressing symptoms of menopausal transition over the intervening 40-year period.

The ten-article collection has been compiled by, and contributed to, by Dr Jeanne Leventhal Alexander, Director, Northern California Kaiser Permanente Psychiatry Women’s Health Program, and Founder of the Alexander Foundation for Women’s Health, a not for profit organization, http://www.afwh.org. The focus of the clinical review collection is to address the likely etiology and treatment of midlife patients who have new complaints or complain of an exacerbation of preexisting complaints in the context of their menopausal transition. The reviews highlight somatic symptoms of depression, the depression continuum and its impact on morbidity and functioning, treatment issues related to remission of depression, cognitive decline or impairment secondary to mood disorder, sleep problems in women and their impact on well-being and functioning, and attention and working memory problems in the vulnerable woman patient. (more…)

Menopausal Women Don’t Get Enough Guidance On Treatment Options, Stanford Survey Shows

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Few women are consulting their doctors before opting to use herbal therapies and soy products to treat their menopausal symptoms, researchers at the Stanford University School of Medicine have found.

The trend is of particular note because growing numbers of women are turning to alternative therapies to relieve such symptoms as hot flashes, headaches, mood swings and sleep disruptions because of concerns about health risks associated with hormone therapy, which is still considered the most effective way of treating such difficulties. The researchers recommend that physicians learn more about these products so that they can help their patients choose safe, effective methods of treating their symptoms.

“We’re not promoting the use of these alternative therapies,” said lead author Jun Ma, MD, PhD, research associate at the Stanford Prevention Research Center. “We’re just saying that the demand for these therapies is growing and that physicians should be prepared to talk to their patients about it.”

The study appears in the May/June issue of The Journal of the North American Menopause Society. The study was funded by GlaxoSmithKline Consumer Healthcare, which had no role in the study design, data collection or preparation of the manuscript for publication. The pharmaceutical company manufactures the herbal product RemiFemin Menopause.

The study was based on a 2004 online survey of a random sample of 781 U.S. women between the ages of 40 and 60. Because the sample size was small, Ma cautioned that the findings may not accurately represent all women, but said the data provide useful insights into women’s attitudes toward menopause treatments and how much physician guidance they have received in deciding which therapies to use.

Among the women surveyed, nine out of 10 reported having experienced at least one menopausal symptom at some point. When it came to treating their symptoms, 37 percent reported using hormone therapy while slightly less than that – 31 percent – used herbal products. Soy supplements were used by 13 percent. (more…)

International Menopause Society Research Team Says HRT Is Safe, Safety Concerns ‘Overhyped’

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The risks associated with hormone replacement therapy are not as great as commonly believed, and women in the early stages of menopause should not worry about taking the drugs, according to Amos Pines, chair of the International Menopause Society, who issued a consensus statement from a team of experts who reviewed the safety and effectiveness of HRT in early menopause, Reuters reports. The statement was issued at a global summit in Madrid on Tuesday (Kahn, Reuters, 5/20).

NIH researchers in July 2002 ended the Women’s Health Initiative study of combination HRT three years earlier than scheduled because they determined that the treatment might increase the risk for heart disease, invasive breast cancer and other health problems (Daily Women’s Health Policy Report, 3/5). The results of the study, which also found HRT increased the risk of ovarian cancer and strokes, caused millions of women to end their use of the drugs.

Pines said that he and colleagues reviewed nu (more…)

Women Believe Menopausal Symptoms Require Treatment With 64% Experiencing Severe Problems

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3rd European Menopause Survey also highlights loss of confidence in HRT and resultant suffering -

More than four out of five women (84%) believe that menopausal symptoms require treatment and should not simply be accepted, according to a survey of over 4200 European women aged 45 to 60 years. However the research – Organon’s 3rd European Menopause Survey – also shows that less than half of women have a positive opinion about hormone replacement therapy (HRT) today and many are unaware of its established benefits.

The survey also reaffirms that the menopause has far-ranging and considerable consequences on women’s lives and indicates that women may be suffering menopausal symptoms but are too concerned about the risk of breast cancer to seek treatment. Women are also unaware of differences between menopausal therapies in relation to the breast.

“These findings provide a fascinating snapshot of women’s views and experiences today. Overall, they highlight the extent of the loss of confidence in HRT, yet clearly demonstrate that the need for treatments to relieve menopausal symptoms is as great as ever,” said Dr Nick Panay, consultant gynecologist, Queen Charlotte’s Hospital, London, UK. “Clearly more must be done to explain both the benefits of therapies and the true risks in order to rebuild women’s confidence in the appropriate use of HRT.”

The European Menopause Survey interviewed more than 4200 women in detail to provide current insights into their views, experiences and needs during and after the menopause. It reaffirms that menopausal symptoms continue to impact the lives of many women. In all, 94 % of women report menopausal symptoms in the last five years, and 64 % report one or more severe menopausal symptoms. Hot flushes were the most common symptom reported by 74 % of women, and have the most impact on women’s lives.

Although most women were aware of HRT, the majority of women have a negative feeling about it. Awareness of their benefits is low. One in five (21%) were unable to name any benefits. By contrast when asked about the main risk factors, 61 % of women say risk of developing breast cancer and 22 % cancer in general.

Half of the women who were on treatment stopped HRT. However, of those who stopped their treatment 42% restarted largely in response to the return of menopausal symptoms. At the same time, 19% of women are currently using natural, herbal or homeopathic treatments including plant estrogens of which clinical effectiveness has never been proven in meta-analysis.

Finally, the findings indicate that one in eight women may be suffering from menopausal symptoms but not using HRT most commonly because of fears about the risk of breast cancer. The proportion of the population suffering without treatment is greatest in Belgium (19%) and France (17%) and lowest in the Netherlands and Spain (both 7%).
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ChiliPad™ Reduces Severity Of Hot Flashes In Menopausal Women

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For many women, the word “menopause” means living with innumerable symptoms which can alter the course of their lives. Menopause affects nearly 40 million women in the United States and while it is a natural time of physical and emotional change, it can also be a time of confusion and worry. Common symptoms include hot flashes, night sweats, insomnia, irritability, low libido, and depression. Hot Flashes are the most common symptom experienced by menopausal women.

ChiliPad™, a revolutionary mattress pad with both heating and cooling functions, reduces the severity of hot flashes by allowing consumers to adjust the entire surface of their bed to the desired temperature. ChiliPad cools and warms a bed from 48 to 118 degrees F.

“Often if a room is too cold for one person it is too warm for the other,” said Todd Youngblood, president and co-founder, ChiliTechnology, LLC. “Some couples resort to opening windows or turning on the AC all night to stay cool. Instead of cooling the whole house to get a comfortable night’s sleep, you can just cool the bed. This is especially helpful for women experiencing hot flashes and night sweats or anyone who just needs to cool their body down to get a good night’s sleep.” (more…)

Increase In Visceral Fat During Menopause Linked With Testosterone

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In middle-aged women, visceral fat, more commonly called belly fat, is known to be a significant risk factor for cardiovascular disease, but what causes visceral fat to accumulate?

The culprit is likely not age, as is commonly believed, but the change in hormone balance that occurs during the menopause transition, according to researchers at Rush University Medical Center.

“Of all the factors we analyzed that could possibly account for the increase in visceral fat during this period in a woman’s lifetime, levels of active testosterone proved to be the one most closely linked with abdominal fat,” said Imke Janssen, PhD, assistant professor of preventive medicine and the study’s lead investigator.

The study, which has been published early online in the medical journal Obesity, included 359 women in menopausal transition, ages 42 to 60, about half black and half white. Fat in the abdominal cavity was measured with CT scans, a more precise measurement than waist size. Blood tests were used to assess levels of testosterone and estradiol (the main form of estrogen). Medical histories covered other health factors possibly linked with an increase in visceral fat.

Statistical analyses showed that the level of “bioavailable” testosterone, or testosterone that is active in the body, was the strongest predictor of visceral fat. (more…)

What Is Menopause? What Are The Symptoms Of Menopause?

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The menopause marks the time in a woman’s life when her menstruation stops and she is no longer fertile (able to become pregnant). In the UK the average age for the menopause is 52 (National Health Service), while in the USA it is 51 (National Institute of Aging). About one fifth of women in India experience menopause before the age of 41, a study found. The menopause is a normal part of like – it is a milestone, just like puberty – it is not a disease or a condition. Even though it is the time of the woman’s last period symptoms may begin many years earlier. Some women may experience symptoms for months or years afterwards.

According to Medilexicon’s medical dictionary, the menopause is the “Permanent cessation of the menses due to ovarian failure; termination of the menstrual life.” (menses = shedding of blood during a woman’s menstrual period). The peri-menopause is the 3 to 5 year period before the menopause when a woman’s estrogen levels begin to drop. Let’s recap the meaning of these two words:

* Menopause – when periods (menstruation) stop forever.
* Peri-menopause – the years before the menopause when estrogen levels start to drop

A study revealed that some British women are in denial when it comes to the menopause.
What are the symptoms of menopause and peri-menopause?
Experts say that technically the menopause is confirmed when a woman has not had a menstrual period for one year. However, the symptoms and signs of menopause generally appear well before the one-year anniversary of the final period. They may include:

* Irregular periods – this is usually the first symptom; menstrual pattern changes. Some women may experience a period every two to three weeks, while others will not have one for months at a time.

* Lower fertility – during the peri-menopausal stage of a woman’s life her estrogen levels will drop significantly, lowering her chances of becoming pregnant.

* Vaginal dryness – this may be accompanied by itching and/or discomfort. It tends to happen during the peri-menopause. Some women may experience dyspareunia (pain during sex). The term vaginal atrophy refers to an inflammation of the vagina as a result of the thinning and shrinking of the tissues, as well as decreased lubrication, caused by a lack of estrogen. About 30% of women experience vaginal atrophy symptoms during the early post-menopausal period, while 47% do so during the later post-menopausal period. There are cases of women who experience vaginal atrophy more than a decade after their final period. The majority of post-menopausal women are uncomfortable talking about vaginal dryness and pain and are reluctant to seek medical help, a study found.

* Hot flashes (UK term: hot flushes)  – this is a sudden feeling of heat in the upper body. It may start in the face, neck or chest, and then spreads upwards or downwards (depending on where it started). The skin on the face, neck or chest may redden and become patchy, and the woman may start to sweat. The heart rate may suddenly increase (tachycardia), or it may become irregular or stronger than usual (palpitations). Hot flashes generally occur during the first year after a woman’s final period.
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